No. One researcher claimed such effects from a study performed on frogs produced from a transgender strain that does not occur in nature, which no one has been able to replicate, that the EPA has dismissed, and that the overwhelming body of evidence contradicts. The sensationalized claim about “atrazine turning frogs gay" popularized by online conspiracy theorists has been debunked.
The controversy traces back to when a professor published several studies suggesting endocrine-mediated responses in amphibians exposed to atrazine, leading to EPA convening a Scientific Advisory Panel in 2003. Subsequent definitive studies, including Kloas et al. (2009), which became the blueprint for EPA's amphibian metamorphosis assay, found no effects on amphibian sexual development at concentrations up to 100 mg/L. Hayes' 2010 study claiming feminization in male African clawed frogs used an artificial “all male” test model that does not exist in nature, and suffered from numerous other scientific flaws. A comprehensive 2019 Quantitative Weight of Evidence analysis published in Critical Reviews in Toxicology concluded that atrazine does not adversely affect fish, amphibians, and reptiles at environmentally relevant concentrations below 0.1 mg/L.
The EPA has further undertaken a comprehensive review of published epidemiology studies examining the potential for reproductive effects or birth defects in the human population. The EPA concluded: “no evidence was found that lead the Agency to conclude that there is a causal association between exposure to atrazine and neuroendocrine toxicity, including increased sensitivity to infants and children.”5